What is the VIPRION® and how is it different from the F5® BIG-IP®? What is the VIPRION? How is it different from F5’s BIG-IP? The VIPRION is BIG-IP! VIPRION is a chassis based, more powerful, and more fault tolerant appliance that runs BIG-IP Traffic Management Operating System® (TMOS®) software – but it’s still BIG-IP at